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KMID : 0043320130360030264
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Archives of Pharmacal Research
2013 Volume.36 No. 3 p.264 ~ p.272
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Multiple biological properties of macelignan and its pharmacological implications
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Paul Saswati
Hwang Jae-Kwan
Kim Hahn-Young
Jeon Won-Kyung
Chung Chi-Hye
Han Jung-Soo
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Abstract
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Macelignan found in the nutmeg mace of Myristica fragrans obtains increasing attention as a new avenue in treating various diseases. Macelignan has been shown to possess a spectrum of pharmacological activities, including anti-bacterial, anti-inflammatory, anti-cancer, anti-diabetes, and hepatoprotective activities; recently, it has also been shown to have neuroprotective activities. This review summarizes the current research on the biological effects of macelignan derived from M. fragrans, with emphasis on the importance in understanding and treating complex diseases such as cancer and Alzheimer’s disease.
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KEYWORD
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Nutmeg, Macelignan, Myristica fragrans, Pharmacological properties, Neurodegenerative disease
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